Virtual Histology and Molecular Environment of Atherosclerotic Plaque by a Novel 3D-Guided Ultrasound Tool for Atherosclerosis Risk Detection.

Plaque composition and histo-molecular mapping - a collaboration between CINQ, Department of Surgery, Biomedical and Molecular Sciences, and QCPU.

The VANGUARD Study uses ultrasound because it is an inexpensive, radiation-free, non-invasive, portable method that could be ideal for imaging the presence of vulnerable plaque before a heart attack or stroke may occur.  To create this new detection tool, our team will be taking 3D ultrasound images from patients undergoing removal of their vessels by our Vascular Surgery department, and analysing this diseased tissue using highly advanced, cutting-edge ultrasound techniques at CINQ and histo-molecular techniques at the Queen’s Cardiopulmonary Unit.

Team on project: Dr. Amer Johri, Dr. Charles Hindmarch, Dr. Stephen Pang, Dr. David Zelt, Dr. Marie-France Hétu, Oliver Jones, Edward Cui, Julia Herr, Christie Boswell-Patterson, Dathan Liblik, and Reem Alzafiri.

Funded by: Queen's University 2019 Translational Medicine Project Operating Grant