Novel Ultrasound-Guided Microcarriers for Atherosclerosis Targeted Therapy (NUGATT)

Ultrasound-guided microcarriers have emerged to treat conditions such as cancer, by delivering therapeutic agents such as genetic vectors, proteins and chemotherapy. The NUGATT program aims at bringing this technology to heart disease through a bilateral collaboration between Queen’s University (Dr. Johri) and Sun Yat-sen University (Dr. Zhou).


  1. Boswell-Patterson CA, Hetu MF, Kearney A, Pang SC, Tse MY, Herr JE, Spence M, Zhou J, Johri AM (2021) Vascularized Carotid Atherosclerotic Plaque Models for the Validation of Novel Methods of Quantifying Intraplaque Neovascularization. JASE (in press)
  2. Huang W, Chen Y, Chen L, Zhong J, Johri A, Zhou J. (2019) Multi-modality Imaging-Guided Local Injection of Eccentric Magnetic Microcapsules with Electromagnetically Controlled Drug Release. Cancer Reports 2(2):e1154.
  3. Tang J, Mi J, Huang W, Zhong H, Li Y, Zhou J, Johri AM. (2018) Controlled drug release from ultrasound-visualized elastic eccentric microcapsules using different resonant modes. Journal of Materials Chemistry B. 6(13).
  4. Yau O, Hétu MF, Herr JE, Adams MA, Johri AM. (2018) Development of a Carotid Vulnerable Plaque Phantom Model Evaluated by Pixel Distribution Analysis. Ultrasound Med Biol. 44(12):2768-2779.
Funded by:

Ontario-China Research and Innovation Fund (OCRIF)

Ontario Centres of Excellence (OCE)

Ministry of Science and Technology of the People’s Republic of China (MOST)