Dr. Amer M. Johri


Dr. Amer Johri is a member of the echocardiography group at Queen’s University and the Director of CINQ. He arrived after completing a research/clinical fellowship in imaging at the Massachusetts General Hospital, Boston, USA under the supervision of Drs. M.H. Picard, J. Hung, and J. Passeri. His clinical interests are in 3D echocardiography, quality control in the echo lab, and interventional echocardiography. He also has extensive experience in echo-guided CRT optimization and TEE guided percutaneous aortic valve replacement.

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Research Interests:

The innovation of non-invasive techniques to predict and diagnose atherosclerotic cardiovascular disease with a focus on three-dimensional carotid ultrasound. Ultrasound is used for: assessment of carotid plaque for early detection of atherosclerotic cardiovascular disease (ACVD), enhancing the stress echocardiogram to better predict significant ACVD, integrating genetic biomarkers to predict ACVD, and monitoring response to treatment of ACVD using novel pharmacologic agents.

Other interests are in 3D echocardiography, strain, quality control in the echo lab, interventional echocardiography, and Hand Held Cardiac Ultrasound.

He serves as an executive member of the ASE Standards and Guidelines Committee is actively participating in the development and review this society's position statement on Hand-Held Cardiac Ultrasound.

Selected Publications

Students are in bold, Supervisors are underlined

  1. Cassels M, Moulson N, Regan J, MacDonald M, Isserow S, Johri AM, McKinney J. (2019) Point‐of‐Care Ultrasound as a Component of Preparticipation Screening of Athletes: A Systematic Review. (in press - Journal of Ultrasound in Medicine).
  2. Grubic N, Baranchuck A, Johri AM (2019) An Athlete’s Journey Through Cardiovascular Screening: Applying a Non-Binary Approach to Sports Participation/Restriction Using Shared-Decision Making. (in press – Can J Cardiol.).
  3. Law TK, Bouck Z, Yin XC, Dudzinski D, Myers D, Nesbitt GC, Edwards J, Yared K, Brian Wong, Hansen M, Weinerman A, Shadowitz S, Farkouh M, Thavendiranathan P, Udell J, Johri A, Chow CM, Rakowski H, Picard MH, Weiner RB, Bathia RS (2019) Association Between Transthoracic Echocardiography Appropriateness and Echocardiographic Findings. J Am Soc Echocardiogr. 32 (5): 667-673.e4.
  4. Mantella LE, Colledanchise KN, MSc, Hétu MF, Feinstein SB, Abunassarb J, Johri AM. (2019) Carotid intraplaque neovascularization predicts coronary artery disease and cardiovascular events. (in press - European Heart Journal - Cardiovascular Imaging).
  5. Johri AM, Grubic N, Kuljic N, O’Connor M, Graham K, Bennett R, Moulson N. (2019) Translation of the Canadian Cardiovascular Society/Canadian Heart Rhythm Society Cardiovascular Screening and Care of Athletes Program into Practice. (in press – Can J Cardiol.).
  6. Herr J, Hétu MF, Li TY, Ewart P, Johri AM. (2019) Presence of Calcium-Like Tissue Composition in Carotid Plaque is Indicative of Significant Coronary Artery Disease in High Risk Patients. J Am Soc Echocardiogr. 32(5):633-642.
  7. Holden RM, Hétu MF , Li TY, Ward E, Couture LE, Herr JE, Christilaw E, Adams MA, Johri AM. (2019) Circulating Gas6 is associated with reduced human carotid atherosclerotic plaque burden in high risk cardiac patients. Clinical Biochemistry. 64:6-11.
  8. Holden RM, Hétu MF , Li TY, Ward E, Couture LE, Herr JE, Christilaw E, Adams MA, Johri AM. (2019) The Heart and Kidney: Abnormal Phosphate Homeostasis is Associated with Atherosclerosis. Journal of the Endocrine Society. 3(1):159–170.
  9. Johri AM, Poirier P, Dorian P, Fournier A, Goodman JM, McKinney J, Moulson N, Pipe A, Taylor T (2019) Canadian Cardiovascular Society/Canadian Heart Rhythm Society Joint Position Statement on the Cardiovascular Screening of Competitive Athletes. Canadian Journal of Cardiology. 35(1):1-11.
  10. Huang W, Chen Y, Chen L, Zhong J, Johri A, Zhou J. (2019) Multi-modality Imaging-Guided Local Injection of Eccentric Magnetic Microcapsules with Electromagnetically Controlled Drug Release. Cancer Reports. 2:e1154.
  11. Mantella LE, Colledanchise K, Bullen M, Hétu MF, Day AJ, McLellan CS, Johri AM. (2019) Handheld Versus Conventional Vascular Ultrasound for Assessing Carotid Artery Plaque. International Journal of Cardiology. 278: 295–299.
  12. Moulson N, Jaff Z, Wiltshire V, Taylor T, O'Connor HM, Hopman WM, Johri AM (2019) Feasibility and Reliability of Non-expert POCUS for Cardiovascular Pre-participation Screening of Varsity Athletes: The SHARP Protocol. Canadian Journal of Cardiology. 35(1):35-41.
  13. Johri AM, Nihal S, Herr J (2018) Why is ASE Helping Lead Cardiovascular Point of Care Ultrasound Education? ASE 7(1).
  14. Patton D, Li TY, Day A, Hétu MF, Day AG, Preece E, Matangi MF, Johri AM. (2018) Speckle Tracking Carotid Artery Circumferential Strain is a Marker of Arterial Sclerosis but not Coronary Atherosis. J Clin Ultrasound. 46(9):575-581.
  15. Yau O, Hétu MF, Herr JE, Adams MA, Johri AM. (2018) Development of a Carotid Vulnerable Plaque Phantom Model Evaluated by Pixel Distribution Analysis. Ultrasound Med Biol. 44(12):2768-2779.
  16. Alexander B, Baranchuk A, Haseeb S, Van Rooy H, Ibrahim O, Kuchtaruk A, Hopman W; Çinier G; Hétu MF; Li T; Johri AM. (2018) Interatrial Block Predicts Atrial Fibrillation in Patients with Carotid and Coronary Artery Disease. J Thorac Dis. 10(7):4328-4334.
  17. Johri AM, Durbin J. (2018) Reply to “Development of a Point-of-Care Cardiovascular Ultrasound Program for Preclinical Medical Students”. Letter to the editor. J Am Soc Echocardiogr. 31(9):1066-1067.
  18. Zhu T, Lavi, S, Johri AM. (2018) Physicians' Attitudes Towards Anticoagulation for Prevention and Treatment of Left Ventricular Thrombus following Anterior Myocardial Infarction. Can J Cardiol. 34(8):1089.e11-1089.e12.
  19. Moulson N, Kuljic N, McKinney J, Taylor T, Hopman WM, Johri AM. (2018). Variation in Preparticipation Screening Medical Questionnaires and Physical Examinations Across Canadian Universities. Can J Cardiol. 34(7):933-936.
  20. Tang J, Mi J, Huang W, Zhong H, Li Y, Zhou J, Johri AM. (2018) Controlled drug release from ultrasound-visualized elastic eccentric microcapsules using different resonant modes. Journal of Materials Chemistry B. 6(13).
  21. Gregg S, Li TY, Hétu MF, Pang SC, Ewart P, Johri AM. (2018) Relationship between Carotid Artery Atherosclerosis and Bulb Geometry. Int J Cardiovasc Imaging. 34(7):1081-1090.
  22. Johri AM, Durbin J, Newbigging J, Tanzola R, Chow R, Sabe De, Tam J. (2018) Cardiac Point of Care Ultrasound: State-of-the-Art in Medical School Education. J Am Soc Echocardiogr. 31(7):749-760.
  23. Patton DM, Enzevaie A, Day A, Sanfilippo A, Johri AM. (2017) A quality control exercise in the echo laboratory: Reduction in inter-observer variability in the interpretation of pulmonary hypertension. Echocardiography. 34(12):1882-1887.
  24. Bhatia RS, Ivers NM, Yin XC, Myers D, Nesbitt GC, Edwards J, Yared K, Wadhera RK, Wu JC, Kithcart AP, Wong BM, Hansen MS, Weinerman AS, Shadowitz S, Elman D, Farkouh ME, Thavendiranathan P, Udell JA, Johri AM, Chow CM, Hall J, Bouck Z, Cohen A, Thorpe KE, Rakowski H, Picard MH, Weiner RB. (2017) Improving the Appropriate Use of Transthoracic Echocardiography: The Echo WISELY Trial. J Am Coll Cardiol. 29;70(9):1135-1144.
  25. Li TY, Tse MY, Pang SC, McLellan CS, King WD, Johri AM. (2017) Sex Differences of the Natriuretic Peptide Polymorphism Associated With Angiographic Coronary Atherosclerosis. Cardiol Res. 8(1):1-6.
  26. Zhu T, DeJong P, Johri AM. (2017) Multiple Spontaneous Coronary Artery Dissections: An Uncommon Cause of Acute Coronary Syndrome in a Syrian Refugee. Can J Cardiol., 33(2):292e13-e15.
  27. Moulson N, Taylor T, Simpson CS, Johri AM. (2017) Current Practices and Attitudes of Canadian Team Physicians Toward Cardiovascular Preparticipation Screening. Can J Cardiol. 33(1):162–165.
  28. Johri AM, Herr JE, Li TY, Yau O, Nambi V. (2017) Novel Ultrasound Methods to Investigate Carotid Artery Plaque Vulnerability. Review. J Am Soc Echocardiogr. 30(2):139-148.
  29. Johri AM, Mantella LE. (2016) Look to Windward: Novel Applications of Vascular Ultrasound. J Am Soc Echocardiogr. 29(11):A23-A24.
  30. Johri AM, Calnan CM, Matangi MF, MacHaalany, J, Hétu MF. (2016). Focused Vascular Ultrasound (FOVUS) for the Assessment of Atherosclerosis: A Proof-of-Concept Study. J Am Soc Echocardiogr 29(9): 842–849.
  31. Wilkinson JS, Barake W, Smith C, Thakrar A, Johri AM. (2016). Limitations of Condensed Teaching Strategies to Develop Hand-Held Cardiac Ultrasonography Skills in Internal Medicine Residents. Can J Cardiol. 32(8):1034-7.
  32. Johri AM, Behl P, Hétu MF, Haqqi M, Ewart P, Day AG, Parfrey B, Matangi MF. (2016) Carotid Ultrasound Plaque Height is a Sensitive Imaging Biomarker for the Assessment of Significant Coronary Artery Disease. Echocardiography 33(2):281-9.
  33. Jozefacki A, White CA, Shobeiri NS, Hopman WM, Johri AM, Adams MA, Holden RM. (2016) Phosphate excretion is decreased in older cardiac patients with ‘normal’ kidney function; an emerging dietary risk factor? Appl Physiol Nutr Metab. 41(4):452-5.
  34. Dunham-Snary KJ, Hong ZG, Xiong PY, Del Paggio JC, Herr JE, Johri AM, Archer SL. (2016) A mitochondrial redox oxygen sensor in the pulmonary vasculature and ductus arteriosus. Pflügers Archiv - European Journal of Physiology 468(1):43-58.
  35. Wang Y, Liu G, Hu H, Li TY, Johri AM, Li X, Wang J. (2015) Stable Encapsulated Air Nanobubbles in Water. Angew Chem Int Ed Engl. 54(48):14291-4.
  36. Al-Turki MA, Patton D, Crean AM, Horlick E, Dhillon R, Johri AM. (2015) Spontaneous Thrombosis of a Giant Left Circumflex Artery Draining Into the Coronary Sinus. Case Report. World J Pediatr Congenit Heart Surg. 6(4):640-2.
  37. Bhatia, RS, Ivers, N, Yin CX, Myers D, Nesbitt G, Edwards J, Yared K, Wadhera R, Wu JC, Wong B, Hansen M, Weinerman A, Shadowitz S, Johri A, Farkouh M, Thavendiranathan P, Udell JA, Rambihar S, Chow C-M, Hall J, Thorpe KE, Rakowski H, Weiner RB. (2015) Design and methods of the Echo WISELY (Will Inappropriate Scenarios for Echocardiography Lessen SignificantlY) study: An investigator-blinded randomized controlled trial of education and feedback intervention to reduce inappropriate echocardiograms. Am Heart J. 170(2):202-9.
  38. Ryan JJ, Huston J, Kutty S, Hatton ND, Bowman L, Tian L, Herr JE, Johri AM, Archer SL. (2015) Right Ventricular Adaptation and Failure in Pulmonary Arterial Hypertension. Can J Cardiology 31(4):391-406.
  39. Johri AM, Chitty DW, Hua L, Marincheva G, Picard MH. (2015) Assessment of image quality in real time three-dimensional dobutamine stress echocardiography: an integrated 2D/3D approach. Echocardiography 32(3): 496-507.
  40. Johri AM, Armstrong DWJ, Jurt U, Brouillard D, Matangi MF. (2014) ICEBERG: Intimal Carotid Evaluation Before Echocardiography Reveals Global Vascular Risk. Can J Cardiology 30(10): 1183-1189.
  41. Johri AM, Heyland DK, Hétu MF, Crawford B, Spence JD. (2014) Carnitine therapy for the treatment of metabolic syndrome and cardiovascular disease: evidence and controversies. Review. Nutr Metab Cardiovasc Dis. 24(8): 808–814.
  42. Barake W, Zardasht J, Najib SS, Hamilton A, Johri AM. (2014) Peri-Aortic Fluid: A Critical Finding In Acute Aortic Syndrome. Echocardiography 31(8): E259-E260.
  43. Johri AM, Hétu MF, Nambi V. (2014) Carotid Plaque or CIMT: What is the future for carotid US imaging? Review. Curr Cardiovasc Risk Rep 8:386-394.
  44. Armstrong DW, Tse MY, Wong PG, Ventura NM, Meens JA, Johri AM, Matangi MF, Pang SC. (2014) Gestational hypertension and the developmental origins of cardiac hypertrophy and diastolic dysfunction. Mol Cell Biochem 391:201–209.
  45. Johri AM. (2014) Generation iUltrasound: Bedside diagnostic imaging with Hand-Held Cardiac Ultrasound. Cardiol J. 21(1):98-9.
  46. Johri AM (2014) One Million Vascular Screening Tests a Year: A Considered Perspective. J Am Soc Echocardiogr. 27(2):A18.
  47. Cawthorn TR, Nickel, C, O’Reilly M, Kafka H, Nair P, Tam, JW, Jackson LC, Sanfilippo AJ, Johri, AM. (2014) Development and evaluation of methodologies for teaching focused cardiac ultrasound skills to medical students. J Am Soc Echocardiogr. 27(3):302-9.
  48. Almehairi M, Baranchuk A, Johri AM, Caldwell J. (2014) An Unusual Cause of Automatic Mode Switching in the Absence of an Atrial Tachyarrhythmia. Pacing and Clinical Electrophysiology 37(6): 777-780.
  49. Johri A, Barake W, Crawford B, Turashvili G, Rossiter J, Evans GA. (2013) The Velvet Myocardium: Potential Harbinger of Death in Acute Myocarditis? Can J Cardiol. 29(12):1742.e25-7.
  50. Caldwell J, Johri AM, Baranchuk A, Redfearn D. (2013) Left ventricle to coronary sinus fistula following ventricular tachycardia ablation. Heart Rhythm 10(10):1556-7. Epub 2012 Jun 29.
  51. Matangi MF, Armstrong DJ, Johri AM, Jurt U, Hollett PM, Del Grande RW, DeYoung JP, Niznick JM, Brouillard DD. (2013) Awareness and use of cardiovascular risk scores by family physicians in southeastern Ontario. Open Journal of Preventive Medicine 3(8): 487-490.
  52. Armstrong DW, Tse MY, O'Tierney PF, Wong PG, Ventura NM, Janzen-Pang JJ, Matangi MF, Johri AM, Croy BA, Adams MA, Pang SC. (2013) Gestational hypertension in atrial natriuretic peptide knockout mice and the developmental origins of salt-sensitivity and cardiac hypertrophy. Regulatory Peptides 186: 108–115.
  53. Johri, AM, Spence, JD. (2013) Barometer in the Storm – Carotid Artery Plaque Quantified by Three-Dimensional Ultrasound. J Am Soc Echocardiogr 26(8): 20A.
  54. Johri AM, Chitty D, Malik P, Matangi M, Malik P, Mousavi P, Day A, Simpson C. (2013). Can Carotid Bulb Plaque Assessment Rule out Significant Coronary Artery Disease? A Comparison of Plaque Quantification by Two- and Three-dimensional Ultrasound. J Am Soc Echocardiogr 26(1):86-95.
  55. Johri AM, Hawthorne KM, Malholtra R, Hung J, Baggish A, Picard MH. (2012). Quality Assessment in Dobutamine Stress Echocardiography: What are the Clinical Predictors Associated with a Non-diagnostic Test? Cardiology Research 3(2):73-79.
  56. Miranda RI, Nault M, Johri AM, Simpson CS, Michael KA, Abdollah H, Baranchuk A, Redfearn DP. (2012). Maximal Electrical Separation-Guided Placement of Right Ventricular Lead Improves Responders in Cardiac Resynchronization Defibrillator Therapy. Circ Arrhythm Electrophysiol. 5:927-932.
  57. Johri AM, Crerar M, Sanfilippo A. (2012). Enhancing the Quality of LVEF Assessment by Echocardiography. US Cardiology 9(1):40-42.
  58. Johri AM, Rojas C, Witzke C, Palacios I, Passeri J, King ME, Abbara S. (2011). Imaging of Atrial Septal Defects: Echocardiographic and CT Correlation. Heart 97(17): 1441-1453.
  59. Jagannath AD, Johri AM, Liberthson R, Larobina M, Passeri JJ, Agnihotri AK. (2011). Quadricuspid Aortic Valve: A Report of 12 Cases and a Review of the Literature. Echocardiography 28(9):1035-40.
  60. Raje NS, Steele DJR, Lawrimore TM, Johri AM, Sohani AR. (2011). Case Records of the Massachusetts General Hospital – Case 29-2011 — A 66-Year-Old Woman with Cardiac and Renal Failure. NEJM 365(12): 1029-1138.
  61. Gilmour J, Kafka H, Ropchan G, Johri AM. (2011). Anomalous Right Coronary Artery: The Multimodality Hunt for the Origin. Case Reports in Cardiology Article ID 286598.
  62. Johri AM, Picard MH, Newell J, Marshall J, King ME, Hung J. (2011). Can a Teaching intervention Reduce Interobserver Variability in LVEF Assessment: A Quality Control Exercise in the Echocardiography Lab. JACCi 4(8):821-9.
  63. Johri AM, Witzke, C, Solis, J, Palacios, IF, Inglessis, I, Picard MH, Passeri JJ. (2011). Real-Time Three-dimensional Transesophageal Echocardiography in Patients with Secundum Atrial Septal Defects: Outcomes following transcatheter Closure. JASE 24(4) 431-7.
  64. Ramirez FD, Johri AM, Kafka H, Smythe J, Sanfilippo AJ, Simpson CS, Redfearn DP, Baranchuk A. (2011). A post-myomectomy heart: 20 years later. Int J Cardiol 150(2):E59-61. Epub.
  65. Johri AM, Passeri JJ, Picard MH. Education in Heart. (2010). Three-Dimensional Echocardiography: Approaches and Clinical Utility. Heart 96(5):390-7.