The Female Risk Factors for post-Infarction Depression and Anxiety (FRIDA) Study was awarded full funding this year by the Heart and Stroke Foundation. 

Led by an interdisciplinary team within the CINQ unit, this is a national program directing sites in Toronto, UBC, Dalhousie, Western, McGill, and Manitoba. Several studies have identified that females are underdiagnosed and undertreated with respect to vascular disease. Female patients are also at higher risk of adverse mental health outcomes following myocardial infarction contributing to the increased morbidity, mortality, and rehospitalization seen in this population. The FRIDA study identifies factors contributing to risk in women. Funding will contribute to expansion of recruitment nationally and seed the development of a local cardiovascular health research program with a focus on female vascular health. 


Several studies have identified that female patients are at higher risk of adverse mental health outcomes following acute myocardial infarction (AMI). These factors have been correlated with increased morbidity, mortality, and rehospitalization. It is not known which female patients are at highest risk for developing depression and anxiety following AMI. Cardiovascular (CV) and sociodemographic risk factors as well as social determinants of health may play a role. The goal of the Female Risk Factors for post-Infarction Depression and Anxiety (FRIDA) Study is to identify which psychosocial and CV risk factors place female patients at highest risk of developing depressive and anxious symptoms following an AMI and to correlate these factors to outcomes at baseline and at 3 and 6 months.


  1. Liblik K, Hu R, Gomes Z, Foldes-Busque G, Mensour E, Sedlak T, Mulvagh SL, Johri AM (2022) Female risk factors for post-myocardial infarction depression and anxiety (FRIDA): Pilot results. Gen Hosp Psychiatry 2022 Sep-Oct;78:138-140.
  2. Liblik K, Théberge E, Gomes Z, Burbidge E, Menon N, Gobran J, Johri AM (2022) Improving Wellbeing After Acute Coronary Syndrome. Curr Probl Cardiol. 7:101201.
  3. Mensour EA, Liblik K, Mantella LE, Johri AM (2022) Depressive Symptoms and Inflammatory Markers Following Acute Myocardial Infarction: A Scoping Review. Health Sciences Review 2: 100020.
  4. Held C, Liblik K, Mulvagh SL, Hindmarch CCT, Alavi N, Johri AM (2021) Emotional distress in women after acute myocardial infarction – still a long way to walk. Trends Cardiovasc Med. 32(6): 348-349.
  5. Liblik K, Mulvagh SL, Hindmarch CCT, Alavi N, Johri AM (2021). Depression and anxiety following acute myocardial infarction in women. Trends Cardiovasc Med 5;S1050-1738(21)00082-7.