Several studies have identified that female patients are at higher risk of adverse mental health outcomes following acute myocardial infarction (AMI). These factors have been correlated with increased morbidity, mortality, and rehospitalization. It is not known which female patients are at highest risk for developing depression and anxiety following AMI. Cardiovascular (CV) and sociodemographic risk factors as well as social determinants of health may play a role. The goal of the Female Risk Factors for post-Infarction Depression and Anxiety (FRIDA) Study is to identify which psychosocial and CV risk factors place female patients at highest risk of developing depressive and anxious symptoms following an AMI and to correlate these factors to outcomes at baseline and at 3 and 6 months.


Liblik K, Mulvagh SL, Hindmarch CCT, Alavi N, Johri AM (2021). Depression and anxiety following acute myocardial infarction in women. Trends Cardiovasc Med 5;S1050-1738(21)00082-7.